Fonds Léon fredericq : De la recherche À la vie

A two-year post-doctoral position available at the University of Brussels

A two-year post-doctoral position (with possibility of extension) is available from February 1st 2018 in the laboratory Dr. Carine Van Lint at the Institute of Molecular Biology and Medicine within the Department of Molecular Biology (DBM) of the University of Brussels (ULB, Belgium).

In Human Immunodeficiency Virus (HIV)-infected individuals on antiretroviral therapy, the persistence of the virus in latently infected cells is thought to be the barrier for cure of infection. The main latent reservoir is constituted of resting memory CD4+ T lymphocytes containing integrated proviruses that are transcriptionally silent. Ongoing studies in the laboratory focus on the role played by epigenetic modifications (such as histone acetylation, histone methylation and DNA methylation) and by non-epigenetic regulatory elements in transcriptional latency and reactivation of HIV-1.

Applicants for this position should have strong background in molecular biology. Prior background in the areas of protein modifications, transcriptional control, epigenetics or biostatistics (ChIP-Seq and RNA-Seq analyses) is an advantage.

Since 1999, the Institute of Molecular Biology and Medicine has brought together over 250 scientists - researchers, professors, PhD graduates, etc. - working in the fields of bacteriology, parasitology, virology, immunology, cancer, embryology, genetics and structural biology. People from the institute also have access to core facilities including cytometry, proteomics and imaging thanks to the neighboring center for microscopy and molecular imaging (CMMI).

Interested candidates should send a cover letter also describing past research experience and CV to Carine Van Lint (cvlint@ulb.ac.be and in cc : sbouchat@ulb.ac.be), together with the name and e-mail address of 2-3 references.